The Institute for Healthcare Improvement (IHI), an independent not-for-profit organization based in Boston, Massachusetts, is a leading innovator, convener, partner, and driver of results in health and health care improvement worldwide. At our core, we believe everyone should get the best care and health possible. This passionate belief fuels our mission to improve health and health care.
Episodes
Thursday Aug 09, 2018
Author in the Room: Antidepressant-Associated Sexual Dysfunction
Thursday Aug 09, 2018
Thursday Aug 09, 2018
September 2008 Author in the Room® Teleconference
Author: H. George Numberg, MD
Summary Points:
- Emergent sexual dysfunction (SD) is a principal reason for a three-fold increased risk of non-adherence that leads to increased relapse, recurrence, and poor disease management outcomes.
- Selective phosphodiesterase-type 5 inhibitors (PDE5Is), limited to studies in men, have demonstrated evidence based data to support broad-based and clinically meaningful treatment efficacy.
- In an intention-to-treat analysis, women treated with sildenafil showed significant improvement in adverse sexual effects compared with those taking placebo.
- Evidence shows that selective phosphodiesterase type 5 inhibitors are effective in both sexes for patients who have been effectively treated for depression but need to continue on their medication to avoid relapse or recurrence.
Version: 20241125
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