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Episodes
Friday Aug 10, 2018
Friday Aug 10, 2018
May 2007 Author in the Room® Teleconference
Author: Jan L. Brandes, MD
Article: "Sumatriptan-Naproxen for Acute Treatment of Migraine"
Summary Points:
- Evidence from two replicate RDBPC trials showed sumatriptan-naproxen as a fixed dose combination was superior in treating an attack of migraine when compared to sumatriptan alone, naproxen alone, or placebo.
- Most importantly, given that migraine attacks in adults are 4 to 72 hours in duration, the fixed dose combination of suma-naproxen was significantly more effective that sumatriptan monotherapy or naproxen monotherapy in providing a 24 hour sustained pain free response.
- Patients using the fixed dose combination therapy were less likely to use rescue medication or to have headache recurrence, and did not experience any penalty in side effects using the combination.
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